New in Science: 7 January 2004

Just posted on www.sciencemag.org:

An editorial by Don Kennedy, kicking off Science's 125th Anniversary year (plus:  PDF editions of Science's first issues).

A new essay series, Global Voices of Science, spotlights views of the scientific enterprise from researchers worldwide.

--From Gonzalez et al.: The number of copies of an anti-HIV factor gene varies among ethnic groups, contributing to their different susceptibilities to HIV infection and AIDS (on Science Express; with accompanying News story).

--From Lohi et al.: A seizure disorder common in such dogs as dachshunds and basset hounds is caused when a 12-nucleotide sequence is repeated in a gene involved in protein degradation.

--From Hall et al.: Analysis of the genomes, transcribed genes, and proteins of two malaria parasites reveals a common set of expressed genes, in addition to others that act in response to specific life-stage pressures.

--From Seshadri et al.: An anaerobic bacterium contains 19 reductive dehalogenases and five hydrogenases, consistent with its unusual ability to dechlorinate pollutants to form nontoxic ethenes.

--From Carvalho and Clark: The genes usually found on the Y chromosome are located elsewhere in one Drosophila species, suggesting that its original Y was dispersed to other chromosomes and the present Y evolved relatively recently (with accompanying Perspective).

--From Indjeian et al.: As half of the DNA is pulled into each daughter cell during division, a protein ensures that the DNA stays attached to the cytoskeleton fibers by monitoring their tension.

--And, from the News Department: Confusion over avian flu; a genomic view of animal behavior; new antimalarials in short supply; and the ethical quandaries of tobacco-related (and -funded) research.